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The HINI virus 2009 may be Biologically Advantageous
The HINI virus 2009 may be biologically advantageous over the seasonal influenza viruses based on animal studies.
Initial findings in ferret suggest that the 2009 HINI influenza virus may “out compete” the seasonal influenza viruses that humans are afflicted with. Tests conducted on animals indicate that the levels of HINI virus tend to rise quicker as compared to the seasonal virus strains. The new virus also caused severe diseases.
Keeping in tune with other findings with other research groups, the University of Maryland researchers observed that the HINI virus was easily transmitted from infected to uninfected to ferrets as compared to the two seasonal influenza viruses.
The researchers did not find any evidence that the HINI 2009 virus when combined with any of the two seasonal viruses to form so-called reassortant viruses. The findings also suggest HINI virus 2009 will probably predominate in the coming flu season. Also there can be biological pressure in order for this new virus to re-combine itself with other circulating viruses say the researchers.
The research was carried out by Daniel Perez, PH.D as well as colleagues belonging to the University of Maryland. The research was also supported by the National Institute of Allergy and Infectious Diseases (NIAID), which is part of the National Institutes of Health.
According to NIAID Director, Anthony S. Fauci, M.D. “This elegant study, conducted in a useful animal model of influenza virus interacts with other flu virus strains. The results suggest 2009 HINI influenza virus may out compete seasonal flu virus strains and may be more communicable as well. These new data, while preliminary, underscore the need for vaccinating against both seasonal influenza and the 2009 HINI influence this fall and winter.”
The findings are posted on PLos Currents: Influenza, Web site meant for rapid communication of newly available scientific data on influenza. The NIAID Centers of Excellence for Influenza Research and Surveillance (CEIRS) program.
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